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Richard J Johnson Selected Research

Metabolic Syndrome (Dysmetabolic Syndrome X)

5/2022Current Hydration Habits: The Disregarded Factor for the Development of Renal and Cardiometabolic Diseases.
1/2022Sirtuin deficiency and the adverse effects of fructose and uric acid synthesis.
11/2021Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor.
9/2021Alternative Dietary Patterns for Americans: Low-Carbohydrate Diets.
9/2021Brief report: The uricase mutation in humans increases our risk for cancer growth.
5/2021Fructose and Uric Acid as Drivers of a Hyperactive Foraging Response: A Clue to Behavioral Disorders Associated with Impulsivity or Mania?
2/2021Osthol Ameliorates Kidney Damage and Metabolic Syndrome Induced by a High-Fat/High-Sugar Diet.
1/2021Umami-induced obesity and metabolic syndrome is mediated by nucleotide degradation and uric acid generation.
10/2020Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease.
3/2020Fructose tolerance test in obese people with and without type 2 diabetes.
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Richard J Johnson Research Topics

Disease

119Hypertension (High Blood Pressure)
01/2022 - 11/2001
67Hyperuricemia
01/2022 - 06/2002
65Metabolic Syndrome (Dysmetabolic Syndrome X)
05/2022 - 12/2005
63Inflammation (Inflammations)
01/2022 - 10/2002
56Chronic Renal Insufficiency
05/2022 - 04/2002
48Obesity
05/2022 - 12/2005
36Proteinuria
11/2021 - 10/2001
32Cardiovascular Diseases (Cardiovascular Disease)
05/2022 - 06/2003
32Fibrosis (Cirrhosis)
10/2021 - 07/2001
31Insulin Resistance
01/2022 - 12/2005
25Gout
01/2021 - 06/2002
23Kidney Diseases (Kidney Disease)
02/2021 - 10/2007
21Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2022 - 07/2009
21Acute Kidney Injury (Acute Renal Failure)
01/2022 - 01/2007
21Dehydration (Water Stress)
01/2020 - 02/2010
21Diabetic Nephropathies (Diabetic Nephropathy)
01/2019 - 01/2003
17Essential Hypertension
01/2020 - 09/2003
17Fatty Liver
01/2019 - 02/2010
17Vascular Diseases (Vascular Disease)
09/2013 - 06/2002
15Albuminuria
12/2020 - 01/2005
14Non-alcoholic Fatty Liver Disease
01/2021 - 06/2008
12Type 2 Diabetes Mellitus (MODY)
09/2021 - 02/2009
11Nephrotic Syndrome (Syndrome, Nephrotic)
11/2021 - 10/2002
10Hypertriglyceridemia
02/2021 - 03/2006
10Dyslipidemias (Dyslipidemia)
03/2020 - 11/2006
9Hypoxia (Hypoxemia)
01/2021 - 06/2002
9Glomerulonephritis
01/2021 - 04/2003
8Lipoid Nephrosis (Glomerulonephritis, Minimal Change)
09/2019 - 11/2009
6Ischemia
10/2021 - 05/2003
6Mitochondrial Diseases (Mitochondrial Disease)
01/2020 - 11/2012
6Chronic Kidney Failure (Chronic Renal Failure)
03/2018 - 04/2005
6Diabetes Mellitus
01/2018 - 11/2006
5Starvation
09/2021 - 01/2009
5Neoplasms (Cancer)
09/2021 - 12/2002
5Kidney Calculi (Kidney Stone)
09/2021 - 09/2011
5Atherosclerosis
11/2020 - 01/2003
5Coronary Artery Disease (Coronary Atherosclerosis)
01/2019 - 01/2005
5Tumor Lysis Syndrome
01/2018 - 10/2009
5Hyperinsulinism (Hyperinsulinemia)
11/2016 - 12/2005
5Pre-Eclampsia (Preeclampsia)
04/2015 - 02/2004
5Arteriolosclerosis
09/2013 - 03/2005
4Myocardial Infarction
01/2022 - 01/2005
4Hyperglycemia
02/2021 - 10/2007
4Body Weight (Weight, Body)
02/2021 - 11/2008
4Disease Progression
12/2019 - 12/2002

Drug/Important Bio-Agent (IBA)

170Uric Acid (Urate)IBA
01/2022 - 06/2002
89FructoseIBA
05/2022 - 12/2005
39SaltsIBA
01/2021 - 11/2001
34CreatinineIBA
01/2022 - 12/2002
30SugarsIBA
05/2021 - 10/2007
25Glucose (Dextrose)FDA LinkGeneric
01/2021 - 03/2006
25Allopurinol (Remid)FDA LinkGeneric
10/2020 - 06/2002
22fructokinaseIBA
02/2021 - 06/2008
19Proteins (Proteins, Gene)FDA Link
01/2021 - 04/2002
18Urate Oxidase (Uricase)IBA
09/2021 - 12/2002
18SodiumIBA
05/2020 - 06/2002
16Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2018 - 10/2001
16Angiotensin IIIBA
11/2014 - 11/2001
15AlbuminsIBA
12/2020 - 11/2008
13Insulin (Novolin)FDA Link
12/2020 - 03/2006
13Oxonic AcidIBA
12/2019 - 06/2002
12Xanthine OxidaseIBA
01/2020 - 12/2002
10EnzymesIBA
02/2021 - 06/2008
10Biomarkers (Surrogate Marker)IBA
10/2020 - 12/2004
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2013 - 07/2001
9Vasopressins (Vasopressin)IBA
05/2022 - 01/2014
9polyolIBA
05/2022 - 01/2014
9Sucrose (Saccharose)IBA
01/2019 - 02/2010
8CarbohydratesIBA
09/2021 - 10/2007
8Adenosine Triphosphate (ATP)IBA
10/2019 - 07/2010
8High Fructose Corn SyrupIBA
01/2019 - 03/2006
8C-Reactive ProteinIBA
08/2017 - 12/2005
8AntioxidantsIBA
01/2015 - 01/2006
7LipidsIBA
01/2021 - 01/2011
7Aldehyde Reductase (Aldose Reductase)IBA
01/2019 - 01/2013
7Triglycerides (Triacylglycerol)IBA
01/2018 - 04/2008
7Messenger RNA (mRNA)IBA
04/2011 - 04/2002
6Blood Glucose (Blood Sugar)IBA
05/2020 - 10/2007
6CollagenIBA
11/2013 - 02/2003
5purineIBA
01/2021 - 12/2006
5HDL CholesterolIBA
01/2018 - 06/2010
5DiureticsIBA
08/2015 - 07/2004
5Drinking WaterIBA
01/2015 - 05/2005
5NitrogenIBA
01/2013 - 10/2001
5Urea (Carbamide)FDA LinkGeneric
01/2013 - 10/2001
5OsteopontinIBA
01/2012 - 03/2002
5Transforming Growth Factor beta (TGF-beta)IBA
10/2005 - 06/2002
5ReninIBA
03/2005 - 09/2002
4LeptinIBA
01/2021 - 11/2008
4NucleotidesIBA
01/2021 - 01/2012
4Oxygen (Dioxygen)IBA
01/2021 - 01/2020
4Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
03/2020 - 01/2018
4Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2020 - 07/2002
4FebuxostatFDA Link
01/2020 - 01/2008
4Phosphates (Orthophosphate)IBA
10/2019 - 11/2006
4CholesterolIBA
02/2019 - 01/2005
4HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
01/2019 - 02/2013

Therapy/Procedure

28Therapeutics
01/2021 - 01/2003
6Nephrectomy
01/2009 - 12/2002
4Kidney Transplantation
12/2020 - 10/2018